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fas receptor การใช้

ประโยคมือถือ
  • Additionally, Titanocene Y is able to induce apoptosis via the FAS receptor pathway.
  • Apoptosis-inducing Fas receptor is dubbed isoform 1 and is a type 1 transmembrane protein.
  • In cultured cells, FasL induces various types of cancer cell apoptosis through the Fas receptor.
  • Furthermore, the Fas receptor also mediates tumor-specific cytotoxic T lymphocyte ( CTL ) anti-tumor cytotoxicity.
  • The Fas receptor is a death receptor on the surface of cells that leads to programmed cell death ( apoptosis ).
  • The AICD effector cell is one that expresses FasL, and apoptosis is induced in the cell expressing the Fas receptor.
  • FAS receptor is located on the long arm of chromosome 10 ( 10q24.1 ) in humans and on chromosome 19 in mice.
  • Infected lymphocytes express the Fas ligand, a cell-surface protein that triggers the death of neighboring uninfected T-cells expressing the Fas receptor.
  • In order for a tumor cell to survive, it must decrease its expression of tumor suppressor genes such as p53, BRCA1, BRCA2, RB1 or the fas receptor.
  • Lack of a functional Fas ligand / Fas receptor system has been linked to abnormal follicle development, and greater numbers of secondary follicles as a result of the inability to induce apoptosis.
  • The term "'death receptor "'refers to those members of the TNF receptor superfamily that contain a death domain, such as TNFR1, Fas receptor, DR5.
  • The Fas receptor ( FasR ) is stimulated by Fas ligand ( FasL ), recruiting FADD to the FasR via an interaction between the death domains ( DD ) of both molecules.
  • Activation-induced cell death ( AICD ) is a programmed cell death caused by the interaction of Fas receptor ( Fas, CD95 ) and Fas ligand ( FasL, CD95 ligand ).
  • The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, Fas receptor-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells.
  • It has been shown that Butyrate inhibits activity of HDAC1 that is bound to the Fas gene promoter in T cells, resulting in hyperacetylation of the Fas promoter and upregulation of Fas receptor on the T cell surface.
  • It has been shown that butyrate inhibits activity of HDAC1 that is bound to the Fas gene promoter in T cells, resulting in hyperacetylation of the Fas promoter and up-regulation of Fas receptor on the T-cell surface.
  • The Fas ligands, or cytotoxicity-dependent APO-1-associated proteins, physically associate with APO-1 ( also known as the Fas receptor, or CD95 ), a tumor necrosis factor containing a functional death domain.
  • The fas receptor ( First apoptosis signal )  ( also known as " Apo-1 " or " CD95 " ) is a transmembrane protein of the TNF family which binds the Fas ligand ( FasL ).
  • Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis.